

Refrigerated and heated benchtop centrifuge
Sigma 4-16KHS
Especially high performance
The Sigma 4‑16KHS refrigerated and heated benchtop centrifuge excels with diverse rotor configurations and outstanding capacity. Large specimen volumes can also be processed efficiently thanks to the maximum capacity of 4 x 750 ml in a swing-out rotor or 6 x 250 ml a fixed-angle rotor. The especially smooth running ensures excellent and reproducible sedimentation results. With its versatile range of rotors, it is suitable for research labs, hospitals, universities and pharmaceutical labs, as well as cell culture and biotechnology applications – especially with specimens whose viscosity must be reduced during centrifugation.
What makes the Sigma 4‑16KHS refrigerated and heated centrifuge so attractive
The Sigma 4‑16KHS is available with numerous swing-out and fixed-angle rotors as well as various buckets and adapters, including many biosafe configurations.
The extensive range of accessories can accommodate tubes and flasks from 0.2 ml to 750 ml as well as microtiter and deepwell plates.
The swing-out rotors can hold up to 3 litres (4 x 750 ml) or (for example) 16 x 50 ml tubes. The RCF values achievable with the configurations are best-in-class in this centrifuge segment. Highlights in the area of fixed-angle rotors include a 6 x 250 ml rotor with a maximum RCF of 13,131 x g and the ability to centrifuge 50 ml culture tubes at more than 23,000 x g.
This compact unit has intuitive operation and well-conceived features. The patented Spincontrol S one-knob controller provides superior operating convenience, safety and versatility. The acceleration and braking profiles (30 each) facilitate optimisation of separation runs and yields. Routine protocols can be stored with user-defined names and quickly retrieved from the integrated process library.
With automatic rotor identification, run time and speed monitoring, password-protected access to the controller and secure program storage, the centrifuge ensures uncompromising safety. The Sigma 4‑16KS also features a high-performance refrigeration system. The temperature adjustment range of the refrigerated and heated centrifuge is –20°C to +60°C.
Swing-out rotor
| max. volume | 3000 ml |
| max. speed | 5,700 rpm |
| max. RCF | 5,485 x g |
Fixed-angle rotor
| max. volume | 1500 ml |
| max. speed | 15,000 rpm |
| max. RCF | 25,155 x g |
Product options
- Inert gas port
- Biosafe swing-out and fixed-angle rotors
- Clinic and cell culture packages
- RS 232 interface
User
- Food labs
- Universities & colleges
- Pharmaceutical labs
- Environmental labs
- Oil industry
Rotors

Swing-out rotor 11660 +
Bucket 13450
| 4 x 750 ml | |
| 5,100 rpm | |
| 5,467 x g |

Swing-out rotor 11650 +
Bucket 13450
| 4 x 750 ml | |
| 4,700 rpm | |
| 4,643 x g |

Swing-out rotor 11150 +
Bucket 13215
| 4 x 200 ml | |
| 5,100 rpm | |
| 5,292 x g |

Swing-out rotor 11156 +
Bucket 13127
| 6 x 200 ml | |
| 4,800 rpm | |
| 4,920 x g |

Swing-out rotor 11118 +
Bucket 13218
| 2 x 93 mm | |
| 5,700 rpm | |
| 5,485 x g |

Swing-out rotor 11150 +
Bucket 13221
| 4 x 56 mm | |
| 5,100 rpm | |
| 4,653 x g |

Swing-out rotor 11660 +
Bucket 13421
| 4 x 61 mm | |
| 4,700 rpm | |
| 3,877 x g |

Swing-out rotor 11650 +
Bucket 13421
| 4 x 61 mm | |
| 4,700 rpm | |
| 3,877 x g |

Fixed-angle rotor 12449
| 48 x 2 ml | |
| 15,000 rpm | |
| 25,155 x g |

Fixed-angle rotor 12201
| 100 x 2 ml | |
| 9,600 rpm | |
| 16,795 x g |

Fixed-angle rotor 12450
| 24 x 5 ml | |
| 13,000 rpm | |
| 21,917 x g |

Fixed-angle rotor 12174
| 24 x 15 ml | |
| 12,000 rpm | |
| 20,285 x g |

Fixed-angle rotor 12269
| 8 x 50 ml | |
| 13,500 rpm | |
| 21,191 x g |

Fixed-angle rotor 12266
| 8 x 50 ml | |
| 14,000 rpm | |
| 21,913 x g |

Fixed-angle rotor 12265
| 6 x 94 ml | |
| 14,000 rpm | |
| 23,228 x g |

Fixed-angle rotor 12356
| 6 x 250 ml | |
| 9,000 rpm | |
| 13,131 x g |
Technical specifications
| Max. capacity [ml] | |
| swing-out rotor | 4 x 750 |
| fixed-angle rotor | 6 x 250 |
| Max. RCF | 25.155 |
| Max. speed [rpm] | 15.000 |
| Min. speed [rpm] | 100 |
| Noise level at maximum speed (approximate) [dB(A)] | |
| fixed-angle rotor 12449 | ≤ 60 |
| swing-out rotor 11660 with bucket 13450 + Cover | ≤ 59 |
| Max. acceleration time [s] | |
| fixed-angle rotor 12449 | ≤ 27 |
| swing-out rotor 11660 with bucket 13450 + Cover | ≤ 23 |
| Max. braking time [s] | |
| fixed-angle rotor 12449 | ≤ 42 |
| swing-out rotor 11660 with bucket 13450 + Cover | ≤ 27 |
| Temperature setting range [°C] | -20 – +60 |
| Power consumption [W] | 2.000 |
| Height x Width x Depth [mm] | 489 x 670 x 650 |
| Height with open lid [mm] | 940 |
| Weight without rotor [kg] | 124 |
| Refrigerant | R452A |
| Charge [kg] / Pressure [bar] | 0,530 / 25 |
| CO2 equivalent [t] | 1,134 |
| Contains fluorinated greenhouse gases in a hermetically sealed refrigeration system. (EU) 2024/2729; 2028-DEC-31. | |













