With the ERWEKA RRT 10, automatic dissolution tests for various extended and sustained release dosage forms are now easier than ever before. This device is perfectly suited to simulate the pH changes within the human body. By placing different media in each row, the device mirrors the different gastrointestinal conditions of the body in vivo.
An automatic sample transport between rows enables reliable extended or sustained release testing of different dosage forms in different pH zones. The easy-to-program RRT 10 is therefore the perfect device for changing the pH of multiple media for IV / IVC testing and dissolution profiling of a variety of prolonged release dosage forms (e.g. tablets, coated tablets and oblongs).
Dissolution Tester BioDis RRT 10 100% USP / EP / JP Compliant
The RRT 10 complies 100 % with USP / EP / JP standards and is available either as USP method 3, USP method 7 or as a combination device of both USP methods. It is equipped with an external flow-through heater that minimizes vibrations on the device. In addition, the device offers a mobile touch display that is easy to operate and enables convenient control.
The vessels are housed in an acrylic water bath with an outlet valve for easy cleaning, and the RRT 10’s automatic cover system reduces evaporation of the media.
Flexible Device for Different Use Cases Product Highlights
100% USP / EP / JP Compliant
As all ERWEKA products, the BioDis RRT 10 is 100 % compliant to USP / EP / JP
Three Configurations Available
USP process 3, USP process 7 and a user-definable combination device for both USP processes
Touch Display for Comfortable Control
Detachable unit with storage space for up to 100 products, media and methods
100% USP / EP / JP Compliant
As all ERWEKA products, the BioDis RRT 10 is 100 % compliant to USP / EP / JP
External Heater
An external flow-through heater reduces the influence of external vibrations and ensures a constant temperature
Touch Display for Comfortable Control
Detachable unit with storage space for up to 100 products, media and methods
Tailored to Your Needs Three Configurations
100 mm Stroke USP 3
- 100 mm stroke height
- 300 & 1000 ml vessel for reciprocating cylinder
- Method not changeable by user
20 mm Stroke USP 7
- 20 mm stroke height
- 50 ml, 100 ml, 300 ml & 1000 ml vessel for different types of tools
- Method not changeable by user
100 mm & 20 mm Stroke USP 3/7
- 100 mm & 20 mm stroke height
- 50 ml, 100 ml, 300 ml & 1000 ml vessels for different types of tools
- Method changeable by user
Dissolution Tester BioDis RRT 10 Options
- 4 racks for 3 test stations each for 1000 ml vessels (USP 3)
- 8 racks for 6 test stations for 50-300 ml vessels
- 8 racks for 7 test stations for 50-300 ml vessels
- Different vessel sizes: 50 ml, 100 ml, 300 ml, 1000 ml
- Evaporation covers for different vessels
- 50 ml vessel, amber glass & adapter ring for 300 ml rack
- Multiple sample holders for both methods
- IQ / OQ documents
Technical Data
| Weight | 50 kg |
| Dimensions (H x W x D) | 690 x 630 x 670 mm |
| Voltage | 110/220/240 V; 50-60 Hz |
| Fuses | 115V/250V, 15A T (slow) 2x 250V, 1A T (slow) / 115V, 2A T (slow) |
| Test stations | 8 rows with 6 stations (standard configuration) and 2 vials for reference purposes or 7 test stations without reference positions |
| Water bath | Water bath of 30 litres volume, clear acrylic glass |
| Thermostat | Heating rate 1500 w, 30-50° C, accuracy +/- 0.2° C |
| Temperature control | External PT 100 temperature sensor |
| Test vessels (standard) | 300 ml USP-compliant cylindrical flat bottomed glass vessels (standard configuration) |
| Test cylinders (USP method 3) | USP-compliant glass reciprocating cylinders fitted with mesh screens of stainless steel or synthetic material (automated centring inside the vessel) |
| Formulation holder (USP method 7) | Whole range of USP-compliant holders for non-eroding formulations made of stainless steel or polytetrafluoroethylene |
| Speed | Speed adjustable from 5-40 strokes/min., accuracy better than +/- 5 % |
| Height of stroke | 100 mm (USP method 3) 20 mm (USP method 7) |
| Evaporation | Vessels protected by automated covering system |
| Control of the unit | Operation by color-touchscreen, password protected access to firmware with OQ functions and product memory |
