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Octet® SF3 SPR device for protein analysis

Octet® SF3 allows users to generate high-quality binding kinetics and affinity data in a fraction of the time, compared to standard multi-cycle or single-cycle kinetics. Combined with user-designed software, the Octet® SF3 device using surface plasmon resonance provides a robust, high-throughput, low-maintenance solution for the rapid characterization of a wide range of biomolecular interactions.

Increased buffer volume

  • holds up to three one-liter bottles, comprising of one water and two buffer lines
  • independently functioning buffer lines, allowing the use of two running buffers to be used during an assay
  • dedicated water line to minimize the risk of buffer precipitation and blockage formation

Optimized fluidics

  • optimized fluidic system, specifically designed to minimize potential sources of blockage
  • system desorb, clean and decontamination protocols ensure maximum system up-time
  • novel fluidic design results in a strong, robust, low maintenance system

Sample recovery

  • recovery of precious samples for further analysis can rapidly decrease workflow times
  • the Octet® SF3 allows the recovery of bound analyte using a predefined Sample Recovery Injection
  • the same analyte can therefore be re-used for alternative analytical techniques

Thermodynamic and Physiological Measurements

  • study interactions across a wide range of temperatures to rapidly assess kinetics and affinity of therapeutics at physiological temperatures
  • in-line buffer degassing prevents air bubble formation and when combined with large syringe volume (700 µl) allows the accurate calculation of dissociation rate constants

 

 

 

 

Documents


Brochure: Octet SF3 Instrument Brochure

Brochure: Octet® SPR Sensor Chips

Brochure: Octet® SF3 SPR Service Plans