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Dissolution Online System UV-Vis

The ERWEKA dissolution online systems are the perfect, semi-automatic solution for dissolution testing with automated UV/VIS online analyses.

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The ERWEKA dissolution online systems are the perfect, semi-automatic solution for dissolution testing with automated UV/VIS online analyses.

The DT 950 with the integrated, automated ASS-9 sampling station transports the freshly sampled media directly to the UV/VIS analyzer (several brands available). There the samples can be measured and the results are then stored in ERWEKA’s sophisticated Disso.NET dissolution software.

ERWEKA offers several types of UV/VIS analyzers, such as the Shimadzu 1900i, the Analytic Jena Specord 210/8 or the Agilent Cary 8454, all combined with our dissolution tester DT 950 and either a peristaltic pump IPC 8 or a PVP piston pump. All components are controlled by the Disso.NET PC software.

 

 

Disso.NET

The ERWEKA Disso.NET software is the perfect 21 CFR Part 11 compliant companion for our dissolution systems. The software provides support for all test methods that can be used with the ERWEKA DT dissolution testers, as well as the automated RoboDis II+.
Disso.NET helps with standard dissolution jobs, handles qualification tasks and provides control over every single function of the connected devices (e. g. dissolution tester, UV-Vis spectrophotometer or HPLC analysis device). The Audit Trail also creates detailed logs of all events and time periods. The software additionally includes an easy-to-use editor for comfortable programming of the dissolution methods (for highest repeatability). After finishing the dissolution test, Disso.NET generates comprehensive reports (as PDF-files) with your corporate logo and/or exports the results (e. g. in XML format).
Disso.NET 4 has an Active Directory connection, allowing for cross-system login data and user passwords. Countless passwords are thus avoided and easy handling is ensured.

 

 

 

 

Proven ERWEKA Quality Throughout Components

Heart of the Dissolution Online System Dissolution Tester DT 950

The DT 950 is the centerpiece of our online system. It is 100% compliant with USP methods 1, 2, 5 and 6, enabling a wide range of dissolution tests to be performed with our system. It also offers the flexible high-head and low-head modes.

Precise Sampling According to USP Sampling Points Automated Sampling Station Ass-9

The automated sampling station ASS-9 is an add-on module for the DT 820 and DT 950. It allows samples to be taken directly from the vessel in accordance with the USP sampling points. These media are then pumped into the FRL 6/7/854 sample collector using the connected pump.

Efficient & Versatile Pump for Erweka Dissolution Systems IPC 8 Peristaltic Pump or PVP 820 Piston Pump

The IPC 8 peristaltic pump offers an accuracy of +/- 0.5 ml and is the basic pump provided with ERWEKA dissolution systems. The PVP piston pump manufactured by Erweka has virtually maintenance-free ceramic heads and is used for high volumes.

Always the Right Solution for Your Needs Versatile UV-Vis Analysis Devices Available

There are several UV/Vis analyzers available for ERWEKA online systems, all fully supported by Disso.NET.

  • Shimadzu 1900i
  • ThermoFischer Evolution Pro
  • Analytica Jena Specord

Advanced Dissolution Software for PC Controlled by Disso.NET

Disso.NET takes full control of ERWEKA online systems. The software offers a sophisticated user management, a wide range of features and comprehensive data export functions.

Easily Adjustable to Your Requirements DT Online System Variants

 

  • DT 9510 series with 12-14 test stations, IPC 16 peristaltic pump and Analytic Jena Specord 210/16 spectrophotometer for UV-Vis analysis
  • Alternatively ERWEKA PVP 620 or 820 piston pump available for filtration up to 0.22 μm

 

 

Dissolution Online System UV-Vis Options

  • Shimadzu 1900i double-beam spectrophotometer with cell changer (8 positions)
  • ThermoFischer Evolution Pro
  • Analytic Jena Specord 200/10
  • IQ / OQ / PV service & documents
  • Maintenance contracts

 

Documents

Dissolution Guide

DT Online Systems

Tablet test equipment overview

 

DT 950

Technical Data

 

Weight 42 kg
Dimensions (H x W x D) 850 x 650 x 650 mm
Voltage 115/230 V; 50/60 Hz
Speed 20-250 U/min
Vessel volume 400 ml / 1000 ml / 2000 ml
Interfaces 1x RS-232, 2x USB, 2x Ethernet/RJ45
Test stations (DT 956) 6 in 2 rows
Test stations (DT 957) 7 in 2 rows
Test stations (DT 958) 8 in 2 rows
USP methods USP 1 / USP 2 / USP 5 / USP 6
Fuses 2 A
Protection class I/EN 61140
Protection type IP 21/IEC 529
Operation Touchscreen 7″, 800×480 Pixel
Sampling positions High-head / Low-head / Cleaning mode
Ambient temperature during operation +10 °C to +30 °C (ambient temperature min. -5 °C below set temperature)
Storage & Transport temp. +5 °C to +40 °C
Relative humidity 25-80 % non condensing

DT 9510

Technical Data

Weight 110 kg
Dimensions (H x W x D) 850 x 1062 x 650 mm
Voltage 115/230 V; 50/60 Hz
Speed 20-250 U/min
Vessel volume 400 ml / 1000 ml / 2000 ml
Interfaces 1x RS-232, 2x USB, 2x Ethernet/RJ45
Test stations (DT 9512) 12 in 2 rows
Test stations (DT 9513) 13 in 2 rows
Test stations (DT 9514) 14 in 2 rows
USP methods USP 1 / USP 2 / USP 5 / USP 6
Fuses 2 A
Protection class I/EN 61140
Protection type IP 21/IEC 529
Operation Touchscreen 7″, 800×480 Pixel
Sampling positions High-head / Low-head / Cleaning mode
Ambient temperature during operation +10 °C to +30 °C (ambient temperature min. -5 °C below set temperature)
Storage & Transport temp. +5 °C to +40 °C
Relative humidity 25-80 % non condensing

PVP Pump x20

Technical Data

Weight 28 kg (for PVP 1220/1420)
Dimensions (H x W x D) 420 x 275 x 575 mm (for PVP 1220/1420)
Voltage 115 V or 230 V, 50/60 Hz
Pump type PVP 1220/1420 (for DT 9510)
Channels 12 or 14 (for PVP 1220/1420)
Valves /
Accuracy +/- 0.5 ml
System compatibility DT Online System, DT Offline System, DT On-/Offline System
Benefits Filtration down to 0.22 μm with a flat membrane filtration. Particularly suitable for fully automatic dissolution systems.

IPC Pump 8/16

Technical Data

Dimensions (H x W x D) 125 x 145 x 220 mm
Interfaces RS 232
Channels 8 or 16
Accuracy 25 ml +/− 5%
Media replacement Standard
Double filtration (optional) Only when first filtration with poroplast filters. No media replacement possible when double filtration.
Required type of sample collector FRL 654 / 754 / 854
System compatibility DT Offline / DT Online / DT On-/Offline
Advantages Basic pump possible with DT 950/9510, needs regular replacement of tubing

Analytik Jena Specord 200

Technical Data

Weight 22 kg
Dimensions (H x W x D) 290 x 590 x 690 mm
Voltage 85–264 V/AC, 50–60 Hz
Optical design Double beam spectrophotometer with fixed spectral bandwidth (Specord 210 with variable spectral bandwidth)
Spectral bandwidth 1.4 nm
Light source Combination of deuterium and halogen lamp
Detector Two silicon photodiodes
Spectrometric system Monochromator with imaging grating and aspherical quartz-coated optics
Baseline deviation ± 0.0005 A (200–1000 nm; slit 1.4 nm)
Zero point transmission ± 0.05 %T (200–1000 nm; slit 1.4 nm)
Wavelength range 190–1100 nm
Wavelength accuracy ± 0.1 nm (Deuterium line at 656.1 nm)
Wavelength reproducibility ≤ 0.02 nm
Wavelength registration speed Up to 12000 nm/min
Wavelength min. data interval 0.02 nm
Photometric range -3 to 3 A
Photometric accuracy UV ± 0.010 A
Photometric accuracy Vis ± 0.003 A
Photometric reproducibility ≤ 0.0005 A
Stray light 198 nm (KCl) ≤ 0.3 %T
Stray light 220 nm (Nal) ≤ 0.03 %T
Stray light 240 nm (Nal) ≤ 0.03 %T
Stray light 340 nm (NaNO2) ≤ 0.02 %T
Baseline noise at 500 nm (RMS) ≤ 0.0001 A

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