Dissolution On-/ Offline System With UV-Vis

Semi-automated dissolution system with connected UV-Vis measurement and sample collection, controlled by Disso.NET.

Semi-automated dissolution system with connected UV-Vis measurement and sample collection, controlled by Disso.NET.

The ERWEKA Dissolution UV-Vis On-/ Offline System is the ideal system configuration for spectrophotometers. With the connected PC, the on-/ offline system can be conveniently controlled via our advanced Disso.NET software. The software also offers full control over all components.

Once the analysis is complete, the samples are conveniently stored using our own FRL 6/7/854 sample collector.

Disso.NET

The ERWEKA Disso.NET software is the perfect 21 CFR Part 11 compliant companion for our dissolution systems. The software provides support for all test methods that can be used with the ERWEKA DT dissolution testers, as well as the automated RoboDis II+.

Disso.NET helps with standard dissolution jobs, handles qualification tasks and provides control over every single function of the connected devices (e. g. dissolution tester, UV-Vis spectrophotometer or HPLC analysis device). The Audit Trail also creates detailed logs of all events and time periods. The software additionally includes an easy-to-use editor for comfortable programming of the dissolution methods (for highest repeatability). After finishing the dissolution test, Disso.NET generates comprehensive reports (as PDF-files) with your corporate logo and/or exports the results (e. g. in XML format).

Disso.NET 4 has an Active Directory connection, allowing for cross-system login data and user passwords. Countless passwords are thus avoided and easy handling is ensured.

Advanced Dissolution System With a Broad Feature Set Product Highlights

100% USP / EP / JP Compliant

Like all ERWEKA products, the dissolution online systems are 100% USP / EP / JP compliant

Easy Control of the Complete System

Full system control of all connected components with the Disso.NET software

USP Methods 1, 2, 5 and 6

Use of a variety of attachments for different USP methods due to the standardized shaft design

Sample Collector FRL 6/7/854

ERWEKA sample collector with up to 8 channels

External Heater

The external flow-through heater reduces the influence of external vibrations and ensures a constant temperature

Advanced UV / Vis Analysis

Different brands of UV / VIS analyzers are available

Proven ERWEKA Quality Throughout Components

  • DT 950
  • DT 9510
  • Sample Collector FRL 6/7/854
  • PVP Pump x20
  • IPC Pump 8/16
  • Automatic Filter Changer AFC 825
  • Analytik Jena Specord 200

Technical Data

Weight42 kg
Dimensions (H x W x D)850 x 650 x 650 mm
Voltage115/230 V; 50/60 Hz
Speed20-250 U/min
Vessel volume400 ml / 1000 ml / 2000 ml
Interfaces1x RS-232, 2x USB, 2x Ethernet/RJ45
Test stations (DT 956)6 in 2 rows
Test stations (DT 957)7 in 2 rows
Test stations (DT 958)8 in 2 rows
USP methodsUSP 1 / USP 2 / USP 5 / USP 6
Fuses2 A
Protection classI/EN 61140
Protection typeIP 21/IEC 529
OperationTouchscreen 7″, 800×480 Pixel
Sampling positionsHigh-head / Low-head / Cleaning mode
Ambient temperature during operation+10 °C to +30 °C (ambient temperature min. -5 °C below set temperature)
Storage & Transport temp.+5 °C to +40 °C
Relative humidity25-80 % non condensing

Technical Data

Weight110 kg
Dimensions (H x W x D)850 x 1062 x 650 mm
Voltage115/230 V; 50/60 Hz
Speed20-250 U/min
Vessel volume400 ml / 1000 ml / 2000 ml
Interfaces1x RS-232, 2x USB, 2x Ethernet/RJ45
Test stations (DT 9512)12 in 2 rows
Test stations (DT 9513)13 in 2 rows
Test stations (DT 9514)14 in 2 rows
USP methodsUSP 1 / USP 2 / USP 5 / USP 6
Fuses2 A
Protection classI/EN 61140
Protection typeIP 21/IEC 529
OperationTouchscreen 7″, 800×480 Pixel
Sampling positionsHigh-head / Low-head / Cleaning mode
Ambient temperature during operation+10 °C to +30 °C (ambient temperature min. -5 °C below set temperature)
Storage & Transport temp.+5 °C to +40 °C
Relative humidity25-80 % non condensing

Technical Data

Weight25 kg
Dimensions (H x W x D)585 x 700 x 515 mm
Channels6,7 or 8
Max. capacity (not for 25 ml test tubes)26 sample intervals
ValveIntegrated 3 way valves
FRL racks26 x 8 / 1.5 ml HPLC vials, 26 x 8 / 4.0 ml HPLC vials, 26 x 8 / 10 ml test tubes, 18 x 8 / 25 ml test tubes
Voltage +- 10%115 – 250 VAC; 50 / 60 Hz

Technical Data

Weight28 kg (for PVP 1220/1420)
Dimensions (H x W x D)420 x 275 x 575 mm (for PVP 1220/1420)
Voltage115 V or 230 V, 50/60 Hz
Pump typePVP 1220/1420 (for DT 9510)
Channels12 or 14 (for PVP 1220/1420)
Valves/
Accuracy+/- 0.5 ml
System compatibilityDT Online System, DT Offline System, DT On-/Offline System
BenefitsFiltration down to 0.22 μm with a flat membrane filtration. Particularly suitable for fully automatic dissolution systems.

Technical Data

Dimensions (H x W x D)125 x 145 x 220 mm
InterfacesRS 232
Channels8 or 16
Accuracy25 ml +/− 5%
Media replacementStandard
Double filtration (optional)Only when first filtration with poroplast filters. No media replacement possible when double filtration.
Required type of sample collectorFRL 654 / 754 / 854
System compatibilityDT Offline / DT Online / DT On-/Offline
AdvantagesBasic pump possible with DT 950/9510, needs regular replacement of tubing

Technical Data

Dimensions (H x W x D)610 mm x 215 mm (without filter refill) or 580 mm (with filter refill) x 200 mm (without valves) or 215 mm (with valves)
Voltage100-240 VAC +/- 10% / 50 and 60 Hz
InterfacesRS 232
Fuses115 V / 250 V, 2 x 3.15 A
Filter requirements– Pore size: 0.22 μm, 0.45 μm, 0.70 μm, 1.0 μm, 10 μm
– Diameter: ≤ 30 mm for automation
Supported filters– PALL Membrane Filter ACRODISC
– Whatman Roby 25 syringe filters for robotic systems
Stations12 valves for 6 stations / 16 valves for 8 stations

Technical Data

Weight22 kg
Dimensions (H x W x D)290 x 590 x 690 mm
Voltage85–264 V/AC, 50–60 Hz
Optical designDouble beam spectrophotometer with fixed spectral bandwidth (Specord 210 with variable spectral bandwidth)
Spectral bandwidth1.4 nm
Light sourceCombination of deuterium and halogen lamp
DetectorTwo silicon photodiodes
Spectrometric systemMonochromator with imaging grating and aspherical quartz-coated optics
Baseline deviation± 0.0005 A (200–1000 nm; slit 1.4 nm)
Zero point transmission± 0.05 %T (200–1000 nm; slit 1.4 nm)
Wavelength range190–1100 nm
Wavelength accuracy± 0.1 nm (Deuterium line at 656.1 nm)
Wavelength reproducibility≤ 0.02 nm
Wavelength registration speedUp to 12000 nm/min
Wavelength min. data interval0.02 nm
Photometric range-3 to 3 A
Photometric accuracy UV± 0.010 A
Photometric accuracy Vis± 0.003 A
Photometric reproducibility≤ 0.0005 A
Stray light 198 nm (KCl)≤ 0.3 %T
Stray light 220 nm (Nal)≤ 0.03 %T
Stray light 240 nm (Nal)≤ 0.03 %T
Stray light 340 nm (NaNO2)≤ 0.02 %T
Baseline noise at 500 nm (RMS)≤ 0.0001 A